Kadın İnfertilitesinde AMH’nin Değerlendirilmesi ve Yorumlanması

Anti-Müllerian hormone (AMH) is a glycoprotein that secreted by the granulosa cells of pre-antral and antral ovarian follicles have diameter <8 mm. By inhibiting both initial recruitments primordial into primary also sensitivity to follicle stimulating (FSH) in cyclic recruitment AMH acts as “follicular gatekeeper”. recognized an early marker decline follicular pool. Although levels are accepted be stable all through menstrual cycle, inter- intracycle variability detected studies with highly sensitive automated assays. Besides aging, body mass index, obesity, oral contraceptive use, previous surgery, chemotherapy, BRCA mutations, ethnicity play role on levels. Polycystic ovary syndrome (PCOS) related increased level thus proposed used diagnostic criterion. However, there no universally threshold value for can diagnosis PCOS. been designing ideal treatment protocol assisted reproduction. measurements utilized prediction poor or hyper response. The pregnancy outcome remains controversial.